The US Food and Drug Administration has approved a new system for nerve repair based on light-activated polymers rather than surgical stitches. The flexible polymer system was developed by the medical technology company Tissium, which was founded over a decade ago to commercialize research from the laboratories of Jeffrey M. Karp and Bob Langer at the Massachusetts Institute of Technology.
Approval is the first for firm Tissium, which was founded over a decade ago by Laura Howes.
Lose an adult tooth, and you’re left with limited options that typically involve titanium implants or plastic dentures. But scientists are working on an alternative: lab-grown human teeth that could one day replace damaged ones.
Pamela Yelick and Weibo Zhang at Tufts University School of Dental Medicine in Boston have grown a mixture of pig and human tooth cells in pieces of pig teeth to create bioengineered structures that resemble real human teeth.
The toothlike structures represent a step toward bioengineered replacements for dental implants, say researchers behind the work.
About one quarter of patients with muscle-invasive bladder cancer (MIBC) may be treated and derive a benefit with the current standard chemotherapy. To better understand why some tumors resist chemotherapy and identify better ways to treat those cancers, researchers at Baylor College of Medicine have conducted a detailed molecular analysis of MIBC tumors. The results, published in Cell Reports Medicine, offer potential new ways to identify which patients will benefit from chemotherapy and reveal possible new treatment strategies.
“One of our goals was to identify molecular markers in patient tumors that would help us predict which patients were most likely to benefit from chemotherapy and which ones might not,” said first co-author, Dr. Matthew V. Holt, director of the Lester and Sue Smith Breast Center Proteomics Laboratory at Baylor.
The researchers studied 60 MIBC tumor samples using a comprehensive multi-omics approach which included genomics (sequencing the genes of the tumor), transcriptomics (analyzing which genes are turned on or off), proteomics (the proteins produced by the tumor) and phosphoproteins (proteins with chemical tags that control their activity).
Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhD
Discount Links/Affiliates:
Blood testing (where I get the majority of my labs): https://www.ultalabtests.com/partners/michaellustgarten.
At-Home Metabolomics: https://www.iollo.com?ref=michael-lustgarten.
Use Code: CONQUERAGING At Checkout.
Clearly Filtered Water Filter: https://get.aspr.app/SHoPY
Epigenetic, Telomere Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7xyIU-LSYLyQdQ6…M0&irgwc=1
Use Code: CONQUERAGING
NAD+ Quantification: https://www.jinfiniti.com/intracellular-nad-test/
Scientists have found a way to supercharge lung cancer treatment by transplanting healthy mitochondria into tumors, which both boosts immune response and makes chemotherapy far more effective. By combining this novel method with cisplatin, researchers reversed harmful tumor metabolism and empowered immune cells to fight back, all without added toxicity.
MIT researchers designed a computationally efficient algorithm for machine learning with symmetric data that also requires fewer data for training than conventional approaches. Their work could inform the design of faster, more accurate machine-learning models for tasks like discovering new drugs or identifying astronomical phenomena.
A new study using 3D modeling software suggests the Shroud of Turin is not the burial cloth of Jesus Christ but a medieval work of art.
CHAMPAIGN-URBANA, Ill. (WCIA) — The U.S. National Science Foundation has awarded a University of Illinois lab $15 million. The money will support the development of AI tools, to help scientists quickly and efficiently synthesize molecules for medicine, energy, industry and more.
The money will be going to the Molecule Maker Lab Institute (MMLI) — which is based on the U of I’s campus, in partnership between Pennsylvania State University and the Georgia Institute of Technology. U of I chemical and biomolecular engineering professor Huimin Zhao directs the lab.
Zhao said functional molecules like drugs chemicals are important in today’s society, but the process of discovering new molecules is slow and expensive. He believes AI can change that.